Adenovirus Diagnostic Testing |
Adenovirus diagnostic testing is the most widely used method
for determining the presence of adenoviruses in a culture of healthy volunteers
and is adapted from the polymerase chain reaction (PCR) method: a procedure by
which DNA strands are broken down into smaller pieces, and then are subjected
to amplification reactions with adenoviruses. Because adenoviruses do not copy
themselves but rather undergo multiple copied copies during viral replication,
several different sequences of adenoviruses will be identified by PCRs. If a
suitable sequence is detected, it will be amplified and the resulting product
isolated.
In the case of patients suspected of having adenovirus, the
adenovirus diagnostic testing is done by a polymerase chain reaction (PCR) test
that can be performed on the patients' blood samples. Adenoviruses that have
been identified by PCR will be identified by the confirmation of specific antibodies
against the virus. These specific antibodies will react against the viral
copies on the strain of adenovirus in the blood samples and will provide an
accurate diagnosis. Patients with suspected AD may be asked to undergo EVGI or
MBO testing, both of which will confirm the diagnosis. Besides, EVGI will also
provide results regarding the presence of a retrovirus in the patients' lymph
nodes, and MBO testing will provide conclusive proof that the patients carry
the retrovirus.
Market
Dynamics
The main factor driving the adenovirus diagnostic testing market is the growth of the treatment monitoring and diagnostic
sector. For instance, according to Policynet, in 2018 the global healthcare
sector generated a revenue of approximately US$ 1.853 trillion. Additionally,
the expansion of the healthcare sectors in the emerging economies is expected
to propel the market growth of adenovirus diagnostic testing. Moreover,
government bodies all over the world are investing in the research and
development of the treatment monitoring market, which is estimated to boost the
market.
However, less knowledge related to various treatments and
diagnostics and the high cost associated with the diagnostic procedures are the
main restraining factors hindering the growth of adenovirus diagnostic testing
market.
This market is distributed in five regions that include
Asia-Pacific, North America, Europe, Africa, and the Middle East, and Latin
America. Among these, North America is expected to a significant share of the
adenovirus diagnostic testing market, owing to the increased expansion of the
healthcare sector and the increasing incidence rate of diseases such as
pneumonia. For instance, according to the Centers for Disease Control and
Prevention, in the U.S. around 1.3 million people suffer from pneumonia. The
adenovirus diagnostic testing market in the Asia Pacific is estimated to
witness significant growth owing to government initiatives for raising
awareness about health concerns.
Competitive Analysis
Key operating in the adenovirus diagnostic testing market
include bioMerieux, Abbott Laboratories, DiaSorin Inc., Qiagen N.V., Novartis
AG, Bio-Rad Laboratories Inc., F. Hoffmann-La Roche AG, Becton Dickinson and
company, and Affymetrix, Inc.
In December 2020, AlloVir announced that the Food and Drug
Administration has given clearance for ALVR106, which is an allogeneic, multi
virus-specific T cell therapy.
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