Anaplastic Astrocytoma Treatment |
High prevalence of brain tumor is expected to propel growth
of the anaplastic astrocytoma treatment market. For instance, according to The
Central Brain Tumor Registry of the United States (2020 CBTRUS Statistical
Report), the incidence rate of all primary malignant and non-malignant brain
and other central nervous system tumors in the U.S was 23.79 cases per 100,000
for a total count of 415,411 incident tumors.
Moreover, R&D of new drugs is also expected to aid in
growth of the market. For instance, in April 2020, Mateon Therapeutics Inc.
announced the publication of a peer-reviewed research article reporting the analysis of the long-term follow-up data on
the recalcitrant/resistant anaplastic astrocytoma patient subpopulation treated
in the NCT00431561 study, in the oncology journal Cancer Reports and Reviews.
Similarly, in December 2020, KIYATEC, Inc. announced the first clinical use of
its response-prediction test to improve outcomes in relapsed brain cancer
patients.
Adoption of combination therapies is expected to offer
lucrative growth opportunities for players in the anaplastic
astrocytoma treatment market. For instance, in January 2021, Adastra
Pharmaceuticals announced that its Phase Ib trial of oral small molecule drug
zotiraciclib in combination with the current standard of care, temozolomide,
deminstrted positive results in the treatment of patients with recurrent
high-grade gliomas (recurrent anaplastic astrocytoma and recurrent
glioblastoma). Moreover, increasing number of treatment centers for brain
tumors is also expected to aid in growth of the market. For instance, in March
2020, MagForce AG, a developer of medical devices that generate magnetic
hyperthermia to treat cancer, and the Hufeland Klinikum GmbH, a provider of
general medical and surgical hospital services, announced the conclusion of a
joint cooperation agreement and the planned opening of a NanoTherm treatment
center for brain tumors at the Mühlhausen site in Thuringia, Germany.
The anaplastic astrocytoma treatment market is witnessing
increasing investment for R&D in the treatment of anaplastic astrocytoma. For
instance, in October 2020, Orbus Therapeutics Inc. raised US$ 71 million in Series
A financing for R&D in the treatment of anaplastic astrocytoma.
Competitive Analysis
Major players operating in the anaplastic astrocytoma
treatment market include, Merck & Co., Inc., Teva Pharmaceutical Industries
Ltd., Adastra Pharmaceuticals, KIYATEC, Inc., Mateon Therapeutics Inc., Orbus
Therapeutics Inc., Mylan N.V., Pfizer, Inc., and Novartis AG.
Major players operating in the anaplastic astrocytoma
treatment market are focused on R&D to expand their product portfolio. For
instance, in March 2021, Orbus Therapeutics Inc. announced a positive outcome
of the pre-planned interim analysis for futility in its Phase 3 STELLAR
clinical study of eflornithine in patients with recurrent anaplastic
astrocytoma.
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