Recombinant
vaccines are made by expressing live viruses as proteins and then creating DNA
sequences out of these viruses. The proteins, or nucleic acid strands, of the
virus, have been repaired with a polymerase that creates a piece of DNA
identical to the rest of the viruses'. These DNA fragments, or polymers, are
injected into the body of a susceptible individual, usually in a vein or in a
garage, through the vein wall. This protects the patient against the deadly
infection caused by the virus. Most commonly used vaccines require one dose of
a product and one dose of a vaccine mixture. This is called a single dose
schedule.
The high prevalence of infectious diseases around the globe is driving the recombinant
vaccines market growth. According to the World Health Organization,
infectious diseases kill over 17 million people a year. An increasing number of
the manufacturer in the recombinant vaccines market is again propelling the
growth of the market. Moreover, advancement in the development of technologies
used in the production of vaccines is further anticipated to foster the growth
of the recombinant vaccines market. Furthermore, continuous investment in
research & development for the production of new vaccines are projected to
fuel the growth of recombinant vaccines.
North America is projected to gain significant growth over the forecast period and this is attributed to the high prevalence of the infectious disease in the region. According to the National Center for Health Statistics, there were around new tuberculosis cases: 9,105, new salmonella cases: 54,285, new Lyme disease cases: 42,743, and new meningococcal disease cases: 353 in 2017.
Key
Developments:
1. In June
2020, Johnson & Johnson announced that through its Janssen Pharmaceutical
Companies (Janssen) it has accelerated the initiation of the Phase 1/2a
first-in-human clinical trial of its investigational SARS-CoV-2 vaccine,
Ad26.COV2-S, recombinant.
2. In November
2020, The European Commission has granted marketing authorization for
Supemtek®, a quadrivalent (four-strain) recombinant influenza vaccine, for the
prevention of influenza in adults aged 18 years and older. Supemtek is the
first and only recombinant influenza vaccine now approved in the European Union.
3. In February
2020, scientists from Hong Kong and Macao special administrative regions
announced a breakthrough in developing a recombinant COVID-19 vaccine
indicating that the mass production of the vaccine is feasible at a low cost in
the future.
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